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Effect of Formaldehyde Inactivation on Poliovirus

Inactivated polio vaccines, which have been used in many countries for more than 50 years, are produced by treating live poliovirus (PV) with formaldehyde. However, the molecular mechanisms underlying virus inactivation are not well understood. Infection by PV is initiated by virus binding to specif...

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Autori principali: Wilton, Thomas, Dunn, Glynis, Eastwood, David, Minor, Philip D., Martin, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178759/
https://ncbi.nlm.nih.gov/pubmed/25100844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-14
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