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Effect of Formaldehyde Inactivation on Poliovirus

Inactivated polio vaccines, which have been used in many countries for more than 50 years, are produced by treating live poliovirus (PV) with formaldehyde. However, the molecular mechanisms underlying virus inactivation are not well understood. Infection by PV is initiated by virus binding to specif...

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Detalhes bibliográficos
Main Authors: Wilton, Thomas, Dunn, Glynis, Eastwood, David, Minor, Philip D., Martin, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178759/
https://ncbi.nlm.nih.gov/pubmed/25100844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-14
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