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Effect of Formaldehyde Inactivation on Poliovirus

Inactivated polio vaccines, which have been used in many countries for more than 50 years, are produced by treating live poliovirus (PV) with formaldehyde. However, the molecular mechanisms underlying virus inactivation are not well understood. Infection by PV is initiated by virus binding to specif...

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Bibliografske podrobnosti
Main Authors: Wilton, Thomas, Dunn, Glynis, Eastwood, David, Minor, Philip D., Martin, Javier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178759/
https://ncbi.nlm.nih.gov/pubmed/25100844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-14
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