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Effect of Formaldehyde Inactivation on Poliovirus

Inactivated polio vaccines, which have been used in many countries for more than 50 years, are produced by treating live poliovirus (PV) with formaldehyde. However, the molecular mechanisms underlying virus inactivation are not well understood. Infection by PV is initiated by virus binding to specif...

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Autores principales: Wilton, Thomas, Dunn, Glynis, Eastwood, David, Minor, Philip D., Martin, Javier
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178759/
https://ncbi.nlm.nih.gov/pubmed/25100844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-14
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