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Effect of Formaldehyde Inactivation on Poliovirus

Inactivated polio vaccines, which have been used in many countries for more than 50 years, are produced by treating live poliovirus (PV) with formaldehyde. However, the molecular mechanisms underlying virus inactivation are not well understood. Infection by PV is initiated by virus binding to specif...

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Bibliografiske detaljer
Main Authors: Wilton, Thomas, Dunn, Glynis, Eastwood, David, Minor, Philip D., Martin, Javier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178759/
https://ncbi.nlm.nih.gov/pubmed/25100844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-14
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