Inhibition of Enterovirus 71 by Adenosine Analog NITD008

Enterovirus 71 (EV71) is a major viral pathogen in China and Southeast Asia. There is no clinically approved vaccine or antiviral therapy for EV71 infection. NITD008, an adenosine analog, is an inhibitor of flavivirus that blocks viral RNA synthesis. Here we report that NITD008 has potent antiviral...

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Bibliografiske detaljer
Main Authors: Deng, Cheng-Lin, Yeo, Huimin, Ye, Han-Qing, Liu, Si-Qing, Shang, Bao-Di, Gong, Peng, Alonso, Sylvie, Shi, Pei-Yong, Zhang, Bo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178731/
https://ncbi.nlm.nih.gov/pubmed/25100827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01207-14
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