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Inhibition of Enterovirus 71 by Adenosine Analog NITD008

Enterovirus 71 (EV71) is a major viral pathogen in China and Southeast Asia. There is no clinically approved vaccine or antiviral therapy for EV71 infection. NITD008, an adenosine analog, is an inhibitor of flavivirus that blocks viral RNA synthesis. Here we report that NITD008 has potent antiviral...

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Main Authors: Deng, Cheng-Lin, Yeo, Huimin, Ye, Han-Qing, Liu, Si-Qing, Shang, Bao-Di, Gong, Peng, Alonso, Sylvie, Shi, Pei-Yong, Zhang, Bo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178731/
https://ncbi.nlm.nih.gov/pubmed/25100827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01207-14
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