Inhibition of Enterovirus 71 by Adenosine Analog NITD008

Enterovirus 71 (EV71) is a major viral pathogen in China and Southeast Asia. There is no clinically approved vaccine or antiviral therapy for EV71 infection. NITD008, an adenosine analog, is an inhibitor of flavivirus that blocks viral RNA synthesis. Here we report that NITD008 has potent antiviral...

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Detalhes bibliográficos
Main Authors: Deng, Cheng-Lin, Yeo, Huimin, Ye, Han-Qing, Liu, Si-Qing, Shang, Bao-Di, Gong, Peng, Alonso, Sylvie, Shi, Pei-Yong, Zhang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178731/
https://ncbi.nlm.nih.gov/pubmed/25100827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01207-14
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