A Monomeric Uncleaved Respiratory Syncytial Virus F Antigen Retains Prefusion-Specific Neutralizing Epitopes

Respiratory syncytial virus (RSV) is the leading infectious cause of severe respiratory disease in infants and a major cause of respiratory illness in the elderly. There remains an unmet vaccine need despite decades of research. Insufficient potency, homogeneity, and stability of previous RSV fusion...

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Bibliographic Details
Main Authors: Swanson, Kurt A., Balabanis, Kara, Xie, Yuhong, Aggarwal, Yukti, Palomo, Concepción, Mas, Vicente, Metrick, Claire, Yang, Hui, Shaw, Christine A., Melero, José A., Dormitzer, Philip R., Carfi, Andrea
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178725/
https://ncbi.nlm.nih.gov/pubmed/25078705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01225-14
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