Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses

Human respiratory syncytial virus (hRSV) vaccine development has received new impetus from structure-based studies of its main protective antigen, the fusion (F) glycoprotein. Three soluble forms of F have been described: monomeric, trimeric prefusion, and trimeric postfusion. Most human neutralizin...

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Vydáno v:J Virol
Hlavní autoři: Palomo, Concepción, Mas, Vicente, Thom, Michelle, Vázquez, Mónica, Cano, Olga, Terrón, María C., Luque, Daniel, Taylor, Geraldine, Melero, José A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934736/
https://ncbi.nlm.nih.gov/pubmed/27009962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00338-16
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