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Tubular p53 Regulates Multiple Genes to Mediate AKI

A pathogenic role of p53 in AKI was suggested a decade ago but remains controversial. Indeed, recent work indicates that inhibition of p53 protects against ischemic AKI in rats but exacerbates AKI in mice. One intriguing possibility is that p53 has cell type-specific roles in AKI. To determine the r...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Dongshan, Liu, Yu, Wei, Qingqing, Huo, Yuqing, Liu, Kebin, Liu, Fuyou, Dong, Zheng
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178437/
https://ncbi.nlm.nih.gov/pubmed/24700871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080902
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