PGC-1α supports glutamine metabolism in breast cancer

BACKGROUND: Glutamine metabolism is a central metabolic pathway in cancer. Recently, reductive carboxylation of glutamine for lipogenesis has been shown to constitute a key anabolic route in cancer cells. However, little is known regarding central regulators of the various glutamine metabolic pathwa...

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Detalhes bibliográficos
Main Authors: McGuirk, Shawn, Gravel, Simon-Pierre, Deblois, Geneviève, Papadopoli, David J, Faubert, Brandon, Wegner, André, Hiller, Karsten, Avizonis, Daina, Akavia, Uri David, Jones, Russell G, Giguère, Vincent, St-Pierre, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178216/
https://ncbi.nlm.nih.gov/pubmed/24304688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-22
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