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IGF-IR Mediated Mammary Tumorigenesis Is Enhanced during Pubertal Development

Although breast cancer typically develops in women over the age of 40, it remains unclear when breast cancer initiating events occur or whether the mammary gland is particularly susceptible to oncogenic transformation at a particular developmental stage. Using MTB-IGFIR transgenic mice that overexpr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jones, Robert A., Watson, Katrina L., Campbell, Craig I., Moorehead, Roger A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178186/
https://ncbi.nlm.nih.gov/pubmed/25259518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108781
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