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ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis
BACKGROUND: The type I insulin-like growth factor receptor (IGF-IR) and ErbB2 (Her-2) are receptor tyrosine kinases implicated in human breast cancer. Both proteins are currently the subject of targeted therapeutics that are used in the treatment of breast cancer or which are in clinical trials. The...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
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BioMed Central
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940847/ https://ncbi.nlm.nih.gov/pubmed/20825649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-235 |
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