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IGF-IR Mediated Mammary Tumorigenesis Is Enhanced during Pubertal Development

Although breast cancer typically develops in women over the age of 40, it remains unclear when breast cancer initiating events occur or whether the mammary gland is particularly susceptible to oncogenic transformation at a particular developmental stage. Using MTB-IGFIR transgenic mice that overexpr...

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Bibliografische gegevens
Hoofdauteurs: Jones, Robert A., Watson, Katrina L., Campbell, Craig I., Moorehead, Roger A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178186/
https://ncbi.nlm.nih.gov/pubmed/25259518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108781
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