Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection

Enteropathogenic and enterohemorrhagic bacterial infections in humans are a severe cause of morbidity and mortality. Although NOD-like receptors (NLRs) NOD2 and NLRP3 have important roles in the generation of protective immune responses to enteric pathogens, whether there is crosstalk among NLRs to...

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Detalhes bibliográficos
Main Authors: Lupfer, Christopher R., Anand, Paras K., Liu, Zhiping, Stokes, Kate L., Vogel, Peter, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178001/
https://ncbi.nlm.nih.gov/pubmed/25254654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004410
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