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microRNA-21-induced Dissociation of PDCD4 from Rictor Contributes to Akt-IKKβ-mTORC1 axis to Regulate Select Renal Cancer Cell Invasion

Renal cancer metastasis may result from oncogenic forces that contribute to the primary tumor. We have recently identified microRNA-21 as an oncogenic driver of renal cancer cells. The mechanism by which miR-21 controls renal cancer cell invasion is poorly understood. We show that miR-21 directly do...

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Autors principals: Bera, Amit, Das, Falguni, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Abboud, Hanna E., Choudhury, Goutam Ghosh
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177976/
https://ncbi.nlm.nih.gov/pubmed/25016284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.06.022
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