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Quinone-Amino Acid Conjugates Targeting Leishmania Amino Acid Transporters

The aim of the present study was to investigate the feasibility of targeting Leishmania transporters via appropriately designed chemical probes. Leishmania donovani, the parasite that causes visceral leishmaniasis, is auxotrophic for arginine and lysine and has specific transporters (LdAAP3 and LdAA...

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Detalhes bibliográficos
Main Authors: Prati, Federica, Goldman-Pinkovich, Adele, Lizzi, Federica, Belluti, Federica, Koren, Roni, Zilberstein, Dan, Bolognesi, Maria Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177859/
https://ncbi.nlm.nih.gov/pubmed/25254495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107994
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