Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development

Haploinsufficiency for Nipbl, a cohesin loading protein, causes Cornelia de Lange Syndrome (CdLS), the most common “cohesinopathy”. It has been proposed that the effects of Nipbl-haploinsufficiency result from disruption of long-range communication between DNA elements. Here we use zebrafish and mou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Muto, Akihiko, Ikeda, Shingo, Lopez-Burks, Martha E., Kikuchi, Yutaka, Calof, Anne L., Lander, Arthur D., Schilling, Thomas F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177752/
https://ncbi.nlm.nih.gov/pubmed/25255084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004671
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