Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture

INTRODUCTION: The goal of the current study was to investigate the effect of aging on the development of endothelial dysfunction in a murine model of sepsis, and to compare it with the effect of genetic deficiency of the endothelial isoform of nitric oxide synthase (eNOS). METHODS: Cecal ligation an...

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Main Authors: Coletta, Ciro, Módis, Katalin, Oláh, Gábor, Brunyánszki, Attila, Herzig, Daniela S, Sherwood, Edward R, Ungvári, Zoltán, Szabo, Csaba
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177582/
https://ncbi.nlm.nih.gov/pubmed/25223540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0511-3
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