CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

BACKGROUND: Recent studies indicated that a synthetic oligonucleotide containing un-methylated CpG oligodeoxynucleotides (CpG-ODN) has a potential function for cancer therapy. In this study, we evaluated the chemosensitizing effects of CpG-ODN in 5-fluorouracil (5-FU)-treated HepG2 human hepatoma ce...

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Bibliographic Details
Main Authors: Liang, Sheng-ran, Hu, Guang-rui, Fang, Li-juan, Huang, Su-jing, Li, Jin-song, Zhao, Ming-yi, Meng, Min-jie
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176997/
https://ncbi.nlm.nih.gov/pubmed/24161202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-106
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