ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice

BACKGROUND & AIMS: ADAM10 is a cell surface sheddase that regulates physiological processes including Notch signaling. ADAM10 is expressed in all intestinal epithelial cell types but the requirement for ADAM10 signaling in crypt homeostasis is not well defined. METHODS: We analyzed intestinal ti...

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Auteurs principaux: Tsai, Yu-Hwai, VanDussen, Kelli L., Sawey, Eric T., Wade, Alex W., Kasper, Chelsea, Rakshit, Sabita, Bhatt, Riha G., Stoeck, Alex, Maillard, Ivan, Crawford, Howard C., Samuelson, Linda C., Dempsey, Peter J.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176890/
https://ncbi.nlm.nih.gov/pubmed/25038433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.07.003
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