A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL

Regulation of transcription is fundamental to development and physiology, and occurs through binding of transcription factors to specific DNA sequences in the genome. CSL (CBF1/Suppressor of Hairless/LAG-1), a core component of the Notch signaling pathway, is one such transcription factor that acts...

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Detalhes bibliográficos
Main Authors: Torella, Rubben, Li, Jinghua, Kinrade, Eddie, Cerda-Moya, Gustavo, Contreras, Ashley N., Foy, Robert, Stojnic, Robert, Glen, Robert C., Kovall, Rhett A., Adryan, Boris, Bray, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176381/
https://ncbi.nlm.nih.gov/pubmed/25114055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku730
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