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Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence

Barcoded vectors are promising tools for investigating clonal diversity and dynamics in hematopoietic gene therapy. Analysis of clones marked with barcoded vectors requires accurate identification of potentially large numbers of individually rare barcodes, when the exact number, sequence identity an...

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Detalhes bibliográficos
Main Authors: Deakin, Claire T., Deakin, Jeffrey J., Ginn, Samantha L., Young, Paul, Humphreys, David, Suter, Catherine M., Alexander, Ian E., Hallwirth, Claus V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176369/
https://ncbi.nlm.nih.gov/pubmed/25013183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku607
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