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Molecular mechanisms of retroviral integration site selection

Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vectors attractive vehicles for human gene-therapy. Though most of the host cell genome is available for integration, the process of integration site selection is not random. Retroviruses differ in their c...

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Bibliografiske detaljer
Main Authors: Kvaratskhelia, Mamuka, Sharma, Amit, Larue, Ross C., Serrao, Erik, Engelman, Alan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176367/
https://ncbi.nlm.nih.gov/pubmed/25147212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku769
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