Dynamics of the Heme-binding Bacterial Gas-sensing Dissimilative Nitrate Respiration Regulator (DNR) and Activation Barriers for Ligand Binding and Escape

DNR (dissimilative nitrate respiration regulator) is a heme-binding transcription factor that is involved in the regulation of denitrification in Pseudomonas aeruginosa. In the ferrous deoxy state, the heme is 6-coordinate; external NO and CO can replace an internal ligand. Using fluorescence anisot...

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Detalhes bibliográficos
Main Authors: Lobato, Laura, Bouzhir-Sima, Latifa, Yamashita, Taku, Wilson, Michael T., Vos, Marten H., Liebl, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176248/
https://ncbi.nlm.nih.gov/pubmed/25037216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571398
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