Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer

Plau codes for the urokinase-type plasminogen activator (uPA), critical in cancer metastasis. While the mechanisms driving its overexpression in tumorigenic processes are unknown, it is regulated by the AP-1 transcriptional complex in diverse situations. The AP-1 component Fra-1 being overexpressed...

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Detaylı Bibliyografya
Asıl Yazarlar: Moquet-Torcy, Gabriel, Tolza, Claire, Piechaczyk, Marc, Jariel-Encontre, Isabelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176185/
https://ncbi.nlm.nih.gov/pubmed/25200076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku814
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