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Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1
Hepatitis C virus (HCV) infection remains a major health problem worldwide. HCV entry into host cells and membrane fusion are achieved by two envelope glycoproteins, E1 and E2. We report here the 3.5-Å resolution crystal structure of the N-terminal domain of the HCV E1 ectodomain, which reveals a co...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175578/ https://ncbi.nlm.nih.gov/pubmed/25224686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5874 |
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