Pushing the limits of sulfur SAD phasing: de novo structure solution of the N-terminal domain of the ectodomain of HCV E1

Single-wavelength anomalous dispersion of S atoms (S-SAD) is an elegant phasing method to determine crystal structures that does not require heavy-atom incorporation or selenomethionine derivatization. Nevertheless, this technique has been limited by the paucity of the signal at the usual X-ray wave...

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Bibliografiske detaljer
Main Authors: El Omari, Kamel, Iourin, Oleg, Kadlec, Jan, Fearn, Richard, Hall, David R., Harlos, Karl, Grimes, Jonathan M., Stuart, David I.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118829/
https://ncbi.nlm.nih.gov/pubmed/25084338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S139900471401339X
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