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Robust Cre-Mediated Recombination in Small Intestinal Stem Cells Utilizing the Olfm4 Locus
The epithelium of the small intestine is the most rapidly self-renewing tissue in mammals. We previously demonstrated the existence of a long-lived pool of cycling stem cells defined by Lgr5 expression at the bottom of intestinal crypts. An Lgr5-eGFP-IRES-CreERT2 knockin allele has been instrumental...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175542/ https://ncbi.nlm.nih.gov/pubmed/25254337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.018 |
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