Llwytho...

Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins

After its discovery as oncogen and morphogen, studies on Wnt focused initially on its role in animal development. With the finding that the colorectal tumour suppressor gene APC is a negative regulator of the Wnt pathway in (colorectal) cancer, attention gradually shifted to the study of the role of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schuijers, Jurian, Clevers, Hans
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380219/
https://ncbi.nlm.nih.gov/pubmed/22617424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.149
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