Direct Stereospecific Synthesis of Unprotected N-H/N-Me Aziridines from Olefins

Despite the prevalence of the N-H aziridine motif in bioactive natural products and the clear advantages of this unprotected parent structure over N-protected derivatives as a synthetic building block, no practical methods have emerged for direct synthesis of this compound class from unfunctionalize...

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Bibliografiske detaljer
Main Authors: Jat, Jawahar L., Paudyal, Mahesh P., Gao, Hongyin, Xu, Qing-Long, Yousufuddin, Muhammed, Devarajan, Deepa, Ess, Daniel H., Kürti, László, Falck, John R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175444/
https://ncbi.nlm.nih.gov/pubmed/24385626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245727
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