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Intramolecular N-Me and N-H Aminoetherification for the Synthesis of N-Unprotected 3-Amino-O-Heterocycles

A mild Rh-catalyzed method for synthesis of cyclic unprotected N-Me and N-H 2,3-aminoethers using an olefin aziridination-aziridine ring-opening domino reaction has been developed. The method is readily applicable to the stereocontrolled synthesis of a variety of 2,3-disubstituted aminoether O-heter...

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Publicado en:Org Biomol Chem
Autores principales: Paudyal, Mahesh P., Wang, Mingliang, Siitonen, Juha H., Hu, Yimin, Yousufuddin, Muhammed, Shen, Hong C., Falck, John R., Kürti, László
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183519/
https://ncbi.nlm.nih.gov/pubmed/33399609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob02122a
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