Mitogen-activated Protein Kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program

The transcription factors Runx2 and Osx (Osterix) are required for osteoblast differentiation and bone formation. Runx2 expression occurs at early stages of osteochondroprogenitor determination, followed by Osx induction during osteoblast maturation. We demonstrate that coexpression of Osx and Runx2...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Artigas, Natalia, Ureña, Carlos, Rodríguez-Carballo, Edgardo, Rosa, José Luis, Ventura, Francesc
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175347/
https://ncbi.nlm.nih.gov/pubmed/25122769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576793
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares