p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation

Osteoblast differentiation is achieved by activating a transcriptional network in which Dlx5, Runx2 and Osx/SP7 have fundamental roles. The tumour suppressor p53 exerts a repressive effect on bone development and remodelling through an unknown mechanism that inhibits the osteoblast differentiation p...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Artigas, Natalia, Gámez, Beatriz, Cubillos-Rojas, Mónica, Sánchez-de Diego, Cristina, Valer, José Antonio, Pons, Gabriel, Rosa, José Luis, Ventura, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686339/
https://ncbi.nlm.nih.gov/pubmed/28777372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.113
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