Runx2/Osterix and Zinc Uptake Synergize to Orchestrate Osteogenic Differentiation and Citrate Containing Bone Apatite Formation

Citrate is essential to biomineralization of the bone especially as an integral part of apatite nanocomposite. Citrate precipitate of apatite is hypothesized to be derived from mesenchymal stem/stromal cells (MSCs) upon differentiation into mature osteoblasts. Based on (13)C‐labeled signals identifi...

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Bibliographic Details
Published in:Adv Sci (Weinh)
Main Authors: Fu, Xuekun, Li, Yunyan, Huang, Tongling, Yu, Zhiwu, Ma, Kun, Yang, Meng, Liu, Qingli, Pan, Haobo, Wang, Huaiyu, Wang, Junfeng, Guan, Min
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908346/
https://ncbi.nlm.nih.gov/pubmed/29721422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201700755
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