Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia

Long-QT syndrome mutations can cause syncope and sudden death by prolonging the cardiac action potential (AP). Ion channels affected by mutations are various, and the influences of cellular calcium cycling on LQTS cardiac events are unknown. To better understand LQTS arrhythmias, we performed curren...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Spencer, C. Ian, Baba, Shiro, Nakamura, Kenta, Hua, Ethan A., Sears, Marie A.F., Fu, Chi-cheng, Zhang, Jianhua, Balijepalli, Sadguna, Tomoda, Kiichiro, Hayashi, Yohei, Lizarraga, Paweena, Wojciak, Julianne, Scheinman, Melvin M., Aalto-Setälä, Katriina, Makielski, Jonathan C., January, Craig T., Healy, Kevin E., Kamp, Timothy J., Yamanaka, Shinya, Conklin, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175159/
https://ncbi.nlm.nih.gov/pubmed/25254341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.06.003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados