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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

Although our knowledge of the biology of brain tumors has increased tremendously over the past decade, progress in treatment of these deadly diseases remains modest. Developing in vivo models that faithfully mirror human diseases is essential for the validation of new therapeutic approaches. Genetic...

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Detalhes bibliográficos
Main Authors: Simeonova, Iva, Huillard, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175043/
https://ncbi.nlm.nih.gov/pubmed/25008045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1675-3
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