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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

Although our knowledge of the biology of brain tumors has increased tremendously over the past decade, progress in treatment of these deadly diseases remains modest. Developing in vivo models that faithfully mirror human diseases is essential for the validation of new therapeutic approaches. Genetic...

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Bibliografiske detaljer
Main Authors: Simeonova, Iva, Huillard, Emmanuelle
Format: Artigo
Sprog:Inglês
Udgivet: Springer Basel 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175043/
https://ncbi.nlm.nih.gov/pubmed/25008045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1675-3
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