RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations

Massively parallel RNA sequencing (RNA-seq) has yielded a wealth of new insights into transcriptional regulation. A first step in the analysis of RNA-seq data is the alignment of short sequence reads to a common reference genome or transcriptome. Genetic variants that distinguish individual genomes...

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Autori principali: Munger, Steven C., Raghupathy, Narayanan, Choi, Kwangbom, Simons, Allen K., Gatti, Daniel M., Hinerfeld, Douglas A., Svenson, Karen L., Keller, Mark P., Attie, Alan D., Hibbs, Matthew A., Graber, Joel H., Chesler, Elissa J., Churchill, Gary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2014
Soggetti:
Multiparental Populations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174954/
https://ncbi.nlm.nih.gov/pubmed/25236449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.165886
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