RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations

Massively parallel RNA sequencing (RNA-seq) has yielded a wealth of new insights into transcriptional regulation. A first step in the analysis of RNA-seq data is the alignment of short sequence reads to a common reference genome or transcriptome. Genetic variants that distinguish individual genomes...

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Auteurs principaux: Munger, Steven C., Raghupathy, Narayanan, Choi, Kwangbom, Simons, Allen K., Gatti, Daniel M., Hinerfeld, Douglas A., Svenson, Karen L., Keller, Mark P., Attie, Alan D., Hibbs, Matthew A., Graber, Joel H., Chesler, Elissa J., Churchill, Gary A.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2014
Sujets:
Multiparental Populations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174954/
https://ncbi.nlm.nih.gov/pubmed/25236449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.165886
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