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The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection
The immune system cannot be continuously reactivated throughout the lifetime of an organism; there is a finite point at which repeated antigenic challenge leads to the loss of lymphocyte function or the cells themselves. Antigen-specific T cells can be compromised in two ways through the distinct pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174864/ https://ncbi.nlm.nih.gov/pubmed/25309548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00468 |
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