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Immune exhaustion during chronic infections in cattle

Recently, dysfunction of antigen-specific T cells is well documented as T-cell exhaustion and has been defined by the loss of effector functions during chronic infections and cancer in human. The exhausted T cells are characterized phenotypically by the surface expression of immunoinhibitory recepto...

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發表在:J Vet Med Sci
Main Authors: KONNAI, Satoru, MURATA, Shiro, OHASHI, Kazuhiko
格式: Artigo
語言:Inglês
出版: The Japanese Society of Veterinary Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289228/
https://ncbi.nlm.nih.gov/pubmed/27725355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.16-0354
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