Cooperation of PD-1 and LAG-3 Contributes to T-Cell Exhaustion in Anaplasma marginale-Infected Cattle

The CD4(+) T-cell response is central for the control of Anaplasma marginale infection in cattle. However, the infection induces a functional exhaustion of antigen-specific CD4(+) T cells in cattle immunized with A. marginale outer membrane proteins or purified outer membranes (OMs), which presumabl...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Okagawa, Tomohiro, Konnai, Satoru, Deringer, James R., Ueti, Massaro W., Scoles, Glen A., Murata, Shiro, Ohashi, Kazuhiko, Brown, Wendy C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038070/
https://ncbi.nlm.nih.gov/pubmed/27430272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00278-16
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