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Toll-Like Receptor Signaling Pathways

Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes. TLRs signal through the recruitment of specific adaptor molecules, leading to activation of the transcription factors NF-κB and IRFs, which d...

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Библиографические подробности
Главные авторы: Kawasaki, Takumi, Kawai, Taro
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174766/
https://ncbi.nlm.nih.gov/pubmed/25309543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00461
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