MicroRNA-128 suppresses prostate cancer by inhibiting BMI-1 to inhibit tumor-initiating cells

MicroRNA-128 (miR-128) is reduced in prostate cancer (PCa) relative to normal/benign prostate tissues but causal roles are obscure. Here we show that exogenously introduced miR-128 suppresses tumor regeneration in multiple PCa xenograft models. Cancer stem-like cell (CSC) associated properties were...

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Detalhes bibliográficos
Main Authors: Jin, Min, Zhang, Tao, Liu, Can, Badeaux, Mark A., Liu, Bigang, Liu, Ruifang, Jeter, Collene, Chen, Xin, Vlassov, Alexander V., Tang, Dean G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174451/
https://ncbi.nlm.nih.gov/pubmed/24903149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0404
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