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The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) eliminates different classes of mRNA substrates including transcripts with long 3′ UTRs. Current models of NMD suggest that the long physical distance between the poly(A) tail and the termination codon reduces the interaction between cytoplasmic poly(A)-binding pro...

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Detalhes bibliográficos
Main Authors: Fatscher, Tobias, Boehm, Volker, Weiche, Benjamin, Gehring, Niels H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174440/
https://ncbi.nlm.nih.gov/pubmed/25147240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.044933.114
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