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Electroencephalographic Power Spectral Density Profile of the Orexin Receptor Antagonist Suvorexant in Patients with Primary Insomnia and Healthy Subjects

STUDY OBJECTIVES: Suvorexant, an orexin receptor antagonist, improves sleep in healthy subjects (HS) and patients with insomnia. We compared the electroencephalographic (EEG) power spectral density (PSD) profile of suvorexant with placebo using data from a phase 2 trial in patients with insomnia. We...

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Bibliographic Details
Main Authors: Ma, Junshui, Svetnik, Vladimir, Snyder, Ellen, Lines, Christopher, Roth, Thomas, Herring, W. Joseph
Format: Artigo
Language:Inglês
Published: Associated Professional Sleep Societies, LLC 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173918/
https://ncbi.nlm.nih.gov/pubmed/25197807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.4068
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