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Discovery and development of orexin receptor antagonists as therapeutics for insomnia
Insomnia persistently affects the quality and quantity of sleep. Currently approved treatments for insomnia primarily target γ-aminobutyric acid-A (GABA-A) receptor signalling and include benzodiazepines and GABA-A receptor modulators. These drugs are used to address this sleep disorder, but have th...
Bewaard in:
| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The British Pharmacological Society
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904252/ https://ncbi.nlm.nih.gov/pubmed/23731216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12261 |
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