Origin Replication Complex Binding, Nucleosome Depletion Patterns, and a Primary Sequence Motif Can Predict Origins of Replication in a Genome with Epigenetic Centromeres

Origins of DNA replication are key genetic elements, yet their identification remains elusive in most organisms. In previous work, we found that centromeres contain origins of replication (ORIs) that are determined epigenetically in the pathogenic yeast Candida albicans. In this study, we used origi...

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Autors principals: Tsai, Hung-Ji, Baller, Joshua A., Liachko, Ivan, Koren, Amnon, Burrack, Laura S., Hickman, Meleah A., Thevandavakkam, Mathuravani A., Rusche, Laura N., Berman, Judith
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173791/
https://ncbi.nlm.nih.gov/pubmed/25182328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01703-14
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