Origin Replication Complex Binding, Nucleosome Depletion Patterns, and a Primary Sequence Motif Can Predict Origins of Replication in a Genome with Epigenetic Centromeres

Origins of DNA replication are key genetic elements, yet their identification remains elusive in most organisms. In previous work, we found that centromeres contain origins of replication (ORIs) that are determined epigenetically in the pathogenic yeast Candida albicans. In this study, we used origi...

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Autores principales: Tsai, Hung-Ji, Baller, Joshua A., Liachko, Ivan, Koren, Amnon, Burrack, Laura S., Hickman, Meleah A., Thevandavakkam, Mathuravani A., Rusche, Laura N., Berman, Judith
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173791/
https://ncbi.nlm.nih.gov/pubmed/25182328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01703-14
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