Origin Replication Complex Binding, Nucleosome Depletion Patterns, and a Primary Sequence Motif Can Predict Origins of Replication in a Genome with Epigenetic Centromeres

Origins of DNA replication are key genetic elements, yet their identification remains elusive in most organisms. In previous work, we found that centromeres contain origins of replication (ORIs) that are determined epigenetically in the pathogenic yeast Candida albicans. In this study, we used origi...

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Detalhes bibliográficos
Main Authors: Tsai, Hung-Ji, Baller, Joshua A., Liachko, Ivan, Koren, Amnon, Burrack, Laura S., Hickman, Meleah A., Thevandavakkam, Mathuravani A., Rusche, Laura N., Berman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173791/
https://ncbi.nlm.nih.gov/pubmed/25182328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01703-14
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